tert-butyl N-[3-fluoro-1-(hydroxymethyl)cyclobutyl]carbamate

Inquire About This Product Request Custom Analogue
tert-butyl N-[3-fluoro-1-(hydroxymethyl)cyclobutyl]carbamate structure
Structural Feature
Cyclobutane scaffold
Reactive Feature
Boc-protected amine Fluorocyclobutane Hydroxymethyl group
Synthesis Role
Fluorinated small-ring building block
Application Context
Pharmaceutical intermediate
CAS Number1232365-48-8
EC/List No.895-601-5
Molecular FormulaC10H18FNO3
Molecular Weight219.25 g/mol
AppearanceWhite solid
SMILESCC(C)(C)OC(=O)NC1(CO)CC(F)C1
InChIKeyMLIXJRTXFCDVNT-UHFFFAOYSA-N
Descriptiontert-Butyl N-[3-fluoro-1-(hydroxymethyl)cyclobutyl]carbamate, a monofluorinated cyclobutane aminomethyl building block. Fluorine tunes conformational preference and metabolic stability.
ApplicationsPharmaceutical intermediate; fluorinated building block; cyclobutane; Boc-protected

Calculated / Predicted Properties

Estimated Boiling Point320.9 °C (predicted)
Estimated Density1.15 g/cm³ (predicted)