(1R,2S)-2-Fluorocyclopropylaminetosylate

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(1R,2S)-2-Fluorocyclopropylaminetosylate structure
Structural Feature
Cyclopropane scaffold
Reactive Feature
Fluorinated building block Primary amine Tosylate salt
Synthesis Role
Chiral fluorinated amine building block
Application Context
Pharmaceutical intermediate
CAS Number143062-84-4
EC/List No.802-120-6
Molecular FormulaC10H14FNO3S
Molecular Weight247.29 g/mol
AppearanceWhite to off-white solid
SMILESCc1ccc(S(=O)(=O)O)cc1.N[C@@H]1C[C@@H]1F
InChIKeyXUWZMHVPMZXIRU-LMLSDSMGSA-N
Description(1R,2S)-2-Fluorocyclopropylamine tosylate, a chiral cis-fluorocyclopropylamine. cis-(1R,2S)-2-fluorocyclopropylamine is the key chiral side-chain amine for sitafloxacin and other fluorinated quinolone antibacterials.
ApplicationsPharmaceutical intermediate; chiral; fluorinated; cyclopropylamine; sitafloxacin side-chain