| CAS番号 | 3680-69-1 |
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| 分子式 | C6H4ClN3 |
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| 分子量 | 153.57 g/mol |
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| 外観 | White crystalline solid |
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| 融点 | 186-189 °C |
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| 沸点 | 325.9 °C (760 mmHg, Predicted) |
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| SMILES | Clc1ncnc2[nH]ccc12 |
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| InChIKey | BPTCCCTWWAUJRK-UHFFFAOYSA-N |
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| 製品説明 | 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine, with 4-chloro as a nucleophilic aromatic substitution handle. Condenses with amines to construct pyrrolopyrimidine drugs; key intermediate for JAK inhibitors like tofacitinib. |
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| 用途 | Pharmaceutical intermediate; pyrrolopyrimidine; JAK inhibitor intermediate |
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| 危険物等級 | Acute Tox. 3 (Oral); Skin Irrit. 2; Eye Irrit. 2; STOT SE 3 (Resp) |
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| 危険有害性情報 | H301; H315; H319; H335 |
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| 注意性情報 | P261; P264; P270; P271; P280; P301+P310+P330; P302+P352; P304+P340; P305+P351+P338; P321; P330; P332+P313; P337+P313; P362; P403+P233; P405; P501 |
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![4-Chloro-7H-pyrrolo[2,3-d]pyrimidine structure](/static/structures/0d62b2e21d365f958928ad66.png)